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By S. R. Rannels, D. E. Rannels

"I. IntroductionThe alveolar surface of the lung is covered by two populations of pneumocytes, type I and type II epithelium. The type I cell, which accounts for most of the alveolar surface area and provides a highly specialized barrier for gas exchange (Rannels et al., 1991), is poorly understood. Although approaches to type I cell purification have been discussed, they have not been applied widely because of the lack of phenotypic markers to monitor isolation procedures (Dobbs et al., 1988; Danto et al., 1992). In contrast, the type II cell has been studied extensively, largely because of the development of reliable procedures for its isolation and primary culture. Investigations based on the use of purified populations of cultured type II cells have provided convincing evidence to support a role for the pneumocytes both in the maintenance of normal lung function and in the response of the lung to injury (for review, see Rannels and Rannels, 1989).While type II cells can be isolated by a variety of approaches, the protocols used most commonly are modifications of the gradient method of Dobbs and Mason (1979) or of the panning method of Dobbs et al. (1986). Purification of the cells based on density gradient centrifugation is reliable and consistent, with yields of 30 to 40 X 106 type II cells per rat of 230 g body weight. Isolation procedures applied to a minimum of three to four rats provide the best results, as lower cell yields are common with the use of fewer animals. The protocol below is designed to obtain a maximal cell yield from the lungs of six rats.II. Materials and InstrumentationMaterialsCalbiochem: DNase I (Cat. No. 260912); Corning: culture flask, 75 cm2 #25115; Costar: culture plate, 24-well #3424; disposable serological pipette #4101; Elastin Products Inc: elastase #E-134; Falcon: cellulose nitrate membrane filter, 0.22 µm, #7105; conical tube, 50 ml, #2070; culture dish, 100 mm, #3003; culture plate, sixwell, #3046; Fisher: BaS04 , #B68-500; NaCl, #5271-3; NaHC03 , #5233-50; Fort Dodge Laboratories: pentobarbital, #1206-lE; Gibco: Dulbecco's minimal essential medium (DMEM), #430-1600EC; Hanks' balanced salt solution (HBSS), #310- 4185AG; Joklik's modified Eagle's medium (JMEM), #410-2300EC; HyClone Laboratories Inc: fetal calf serum (FCS ), # A-1115-L; I CN Biochemicals (Flow Labora tories): amphotericin B, #16-723-48; newborn calf serum (NCS), #29-121-54; try pan blue, # 19 5 5 32; Na/gene: Erlenmeyer flask, # 100-4116C; Pharmacia: Percoll, #17-0891-01; density marker beads, #17-0549-01; Sigma: gentam1cm sulfate, #G3632; penicillin/streptomycin, #P3539; trypsin inhibitor, #T9128; Tetko: HC- 160 nylon mesh, #3-160-53."

Dec 1, 1995

The paper point out the testwork has been carried out with real process solutions from the Chambishi cobalt plant in Zambia, showing that the ISEP® continuous ion exchange system can effectively remove nickel from cobalt sulphate electrolyte. Laboratory testing confirmed published data, and was subsequently verified on site at Chambishi in a pilot test program. Based on the testwork data, a commercial unit is being installed at Chambishi.

Sep 13, 2001

By T. R. Achenbach

1. This, the final report to the U. S. Bureau of Mines on the program with the subject title, presents the data obtained from June 29, 1973, to April 20, 1974. 2. Operating in the Illinois #6 coal seam, the effectiveness of foam opposed to water was compared in reducing respirable coal dust. A combination of 39 foam generators and 14 water sprays were used during the foam tests. Sixty one water sprays were operated during the water tests. Data from 24 shifts using foam and 21 shifts using water are presented. 3. Additional work on foam generator design should be undertaken to provide coverage to a wider area with foam. 4. The general attitude of those working on the foam program and with the miner at the face was positive. It is urged that the work be continued. 5. The minor respiratory irritations evidently caused by an aerosol effect of the surfactant should be investigated. 6. The statistical analysis of the tests will be made and reported by the U. S. Bureau of Mines.

Jan 1, 1974

Copper, zinc, lead, and silver in the discordant magmatic-hydrothermal orebody of the Conrad Mine, N.S.W., all have a relatively high mean abundance. Any single concordant sulphide orebody containing the same metals has a similar order of mean abundance of only one or two of these, particularly copper, copper and zinc, or zinc and lead.The relative abundances of the metals in the Conrad orebody vary more widely than in concordant orebodies, and the lead-zinc-silver and copper-zinc-lead relationships are significantly different.INTRODUCTIONIn previous investigations of metal abundances in sulphide ores, the basis of selection of the orebodies was their form, and to some extent their geological setting, rather than hypotheses concerning their origin. In all cases they were generally concordant with the bedding of the sedimentary or meta-sedimentary rocks enclosing them, and most occurred in volcanic-sedimentary sequences. Their mineralogies were simple, and they were copper, copper-zinc, zinc or lead-zinc rich in composition. Most were of the type ascribed by several authors to exhalative-sedimentary processes.In one of these investigations (Stanton, 1958), it was pointed out that since the metals in ores of this type showed similar abundance patterns and behaviour, it would clearly be of interest to examine, and to compare with them, orthomagmatic and vein types, unquestionably derived from their igneous rock associates.The present investigation is concerned with a single orebody, of clearly discordant type, and of indisputable hydrothermal origin. The abundance and behaviour of copper, zinc, lead, and silver have been determined and compared to similar data fOl!' the concordant type. Such a comparison tests the possibility that metal abundance patterns of base metal ores may be indicative of the mode of ore deposition.

Jan 1, 1963

By J. Szekely, S. Rhee

"A mathematical formulation has been presented to describe heat and fluid flow phenomena in CVD operations. In the statement of the problem, which included consideration of plasma enhanced CVD systems, emphasis was placed on identifying the parameters which play a key role in determining the rate and the spatial uniformity of the deposition process. This was done both through the appropriate dimensionless groups and by presenting an extensive set of computed results. The main conclusions that may be drawn from this work are that the deposition rate will be inherently non-uniform for atmospheric CVD systems; this may be somewhat ameliorated by inclining the susceptor or changing the vessel contours. Operation at greatly redeced pressures and for PECVD systems will give a much more spatially uniform deposition rate.1. INTRODUCTIONIn recent years, there has been a growing interest in chemical vapor deposition techniques for the preparation of thin films for semiconductor, photovoltaic applications and for coatings in general, as evidenced by numerous journal articles and symposium proceedings devoted to this topic (1-6). An interesting variant of this technique is to perform the deposition in a plasma or glow discharge at low pressures because this technology obviates the need for the thermal decomposition of the precursor at the substrate surface and permits operation at greatly reduced temperatures (7-10).By far, the largest portion of the reported work dealing with both these aspects of the technology has been concerned with the characterization of the deposit, quite properly so. However, in more recent times it has been realized that the transport aspects of these processes are also deserving of attention because the understanding of heat flow, fluid flow and diffusional phenomena may provide the key to the solution of problems associated with obtaining uniform deposits and the proper scaling of laboratory measurements in order to design industrial CVD systems."

Jan 1, 1986

By R. T. Langland

Using a finite-element computer model, we have conducted an analytical study of roof behavior in a room-and-pillar coal mine. With standard engineering property in formation and a computer code developed for the Bureau of Mines to calculate roof sag, convergence, and roof-bolt load change, we have calculated the stability of roof-support systems and compared the computed data with experimental data collected during a field investigation at three test sites, one in a development area and two in production areas of a coal mine.

Jan 1, 1978

By Samuel M. Bryant

The purpose of this study was to develop procedures to measure Bingham flow properties for mine tailings and to use these to predict the possible consequences of a hypothetical tailings flow failure at the Tenmile Tailings Pond at Climax, Colorado. The consequences of such a failure were found to be minimal, and the failure itself highly; unlikely. Values of Ty (Bingham yield shear strength) and np (plastic viscosity) were measured for 10 materials using results obtained from vaned coaxial viscometer tests and triaxial tests.

Jan 1, 1983

By Wang Zhi

High-Mg-content concentrates are usually treated in Jinchuan flash smelting Furnace. Because the viscosities of high-Mg-content slag is very high, the operation of flash smelting becomes very difficult. To solve this problem, the viscosities of the semi-synthesized FeO-MgO-SiO2 slag of different compositions were measured. The results showed that when in the slag the weight percentage of MgO [w(MgO)] is 6-10%, the ratio of the weight percentage of iron to that of Si02, w(Fe)/w(Si02) is 1.1-1.4 and the temperatures are within 1473-1773K, the slag viscosities increased with the increase of W(MgO) and w(Fe)/w(SiO,). When w(Mgo)<6%, the smelting temperature should be controlled at I 300°C in order to to keep the smooth operation. When w(MgO)>10%, the temperature should be kept above I 633K. When the content of MgO is higher, a lower viscosity slag can be produced by decreasing the ratio of w(Fe)/w(SiO,). The appropriate ratio of w(Fe)/w(SiO,) for Jinchuan flash smelting furnace is about 1.2.

Jan 1, 2003

By R. T. C. Rasmussen

"INTRODUCTION This is the second report of investigations describing tests in full-scale commercial heats of steel-using electrolytic manganese having a purity of about 99.95 percent, produced in the Bureau's pilot plant at Boulder City, Nev. The first report dealt with tests in cooperation with two companies can the use,of electrolytic manganese in the manufacture of stainless steel. 3/ Plans aril cost estimates for reasonably large commercial, electrolytic plants based upon pilot-plant experience, as well as the comments of a number of concerns where electrolytic manganese has been tried, are contained in another publication.4/ The tests in cooperation with industry are part of the Bureau of Mines program of investigations of methods of utilizing low-grade domestic manganese ores, thereby the United States leas dependent upon foreign sources of manganese for metallurgical use. The Boulder City pilot plant already has demonstrated the feasibility of producing electrolytic manganese from several of the most important reserves of low-grade manganese ore. As the ferromanganese normally used by the steel industry represents the bulk of the Nation's manganese requirements, the usefulness and possi¬ble advantages of electrolytic manganese in the manufacture of steel must be established if electrowinning from domestic ores is to become an important factor of manganese supply.Preliminary arrangements for the cooperative tests at the Atlas Steel Casting Co., Buffalo,. N. Y., were made with E. L. Altenburg, vice president and general manager of the company, by A. A. Dow. 5/ The data on the tests at the Atlas plant presented herein are based upon reports of E. L. Altenburg and information obtained by the author during a visit to the plant to observe the initial trial heats with electrolytic manganese in the open-hearth and the electric furnace."

Nov 1, 1945

By Milan Terčelj, Matej Drobne, Urška Klančnik, Peter Fajfar

The study of oxidation behavior of High Chromium Steel material used for surface layer of work rolls was carried out. Specimens taken directly from the roll were subjected to thermal fatigue in the temperature range between room temperature and 500 °C up to 700 °C by using thermo-mechanical simulator Gleeble 1500D. Our observation was focused on the impact of oxidation as a principal mechanism of degradation of the roll’s surface layer - mainly on the characteristics of oxidation propagation in relation to the test temperature and microstructure constituents characteristics of the material. Oxidation is considerably accelerated by certain characteristics of eutectic and primary carbides, i.e. their size (area), composition, morphology, orientation regarding to the water-cooled surface, etc. In the presented paper selected cases where emphasized oxidation takes place are investigated, analyzed and explained. Obtained results thus represent a contribution to explanation of conditions which lead to acceleration of oxidation behavior that in turn can lead to chipping or even early spalling of material from the roll surface layer.

Oct 1, 2019

Several economic factors have caused the surface mining industry to require large-capacity shovels and trucks for efficient, high-production, low-cost operations. Some of those factors include technological advancements in equipment, commodity market depressions, increased labor and maintenance costs, contractural obligations and harsh operating conditions. The difficult operating conditions in surface mines, however, pose challenges to the use of high-capacity equipment. They include space limitations, weak over-burden, and weathered soils and rocks. So mining companies face major challenges in selecting appropriate shovels to meet the technical, operating, safety, environmental and economic requirements of their mines.

Jan 1, 2003

Most processing plants use automatic samplers to extract ore aliquots along a producing shift. These aliquots are combined into a sample normally sent to lab analysis. The sampler used in the extraction of an aliquot from a continuous flow of ore, i.e. a belt conveyor is required to be both precise and accurate. Surprisingly, not all commercial automatic samplers exhibit these two mandatory properties. Consequently, it is recommended the development of a procedure able to check sample assays reproducibility obtained using a given sampling protocol. This paper uses the Gy’s sampling theory to evaluate coal quality control practices at a washing plant using an automatic sampler extracting coal increments from the ROM feeding belt conveyor. Gy’s theory provides the means to establish the precision limits for a given sampling protocol. Various ore properties are required to be determined in combination with sample mass and mass of the lot sampled. All this information leads to the definition of the precision limit. The precision limit obtained was checked via an experiment mimicking what happens in situations where both miner and consumer use the same and appropriate sampling practices. The experiment demonstrates that sampling theory precision limits were valid if unbiased samplers are used by both parties, i.e. miner and consumer. Keywords: sampling, quality control, coal

Jan 1, 2003

By J. P. McGee

The Bureau of Mines is doing research and development work on a coal-fired gas turbine plant initially developed by the Locomotive Development Committee, (LDC) of Bituminous Coal Research, Inc. The Bureau is redesigning the turbine blading and some of the auxiliary equipment, and is reerecting, the plant at the Morgantown (W. Va.) Coal Research Center. The present goal is a 1,500-hour run at virtually the same operating conditions used by the LDC in their final 1,100-hour test with the turbine. This will allow the Bureau to properly evaluate the new blade design. Erosion of the turbine blades (particularly the roots) by ash in the hot gases from the combustion of coal was the most serious problem in extended operation in earlier experimental work. New blades made of Stellite6 are being fabricated for the stator and rotor, and armored wear strips of titanium carbide will be inserted in the blades at the areas of probable maximum ash velocity and concentration. The trailing edges of the rotor and stator blades are being thickened and thinned, respectively, to induce the ash to travel to the casing and prevent it from returning to the base of the rotor blades. The first stage rotor and second stage stator blades are being removed to provide an annular space for maximum quantities of coal ash to centrifuge to the casing. Additional blades will be added to most of the rows in the stator to stop secondary flow of dust-laden gas toward the rotor. A contract has been awarded for fabrication of the new blades. The 1,500-hour run will be started as soon as the new blades are installed.

Jan 1, 1962

Mixed integer programming (MIP) has been used for optimizing production schedules of mines since the 1960s. The major problem in the long-term production scheduling for an entire orebody is that the number of integer variables needed to formulate an MIP model is too large to solve the formulation. This number may reach well over one hundred thousand. To overcome this difficulty, this paper presents two new algorithms to reduce the size of the problem. These algorithms assign an earliest and latest possible start date for each machine placement, eliminating the integer variables that correspond to machine placement before its early start date and after its late start date. A case study based on Kiruna Mine, the second largest underground mine in the world, is summarized in the paper. It shows substantial improvement in the solution time required using the new algorithms. This increased efficiency in the solution time of the MIP model allows it to be applied to Kiruna Mine, with the potential to increase substantially the net present value (NPV) of the project.

Jan 1, 2008

For the first time in its history, the George A. Fox Conference let its focus venture away from the friendly confines of the East Coast of the United States to spend part of the one-day conference looking at projects from around the globe. With a record-setting attendance of 377 people, the conference, titled ?Tunneling: An international perspective,? opened with a keynote speech from special guest In-Mo Lee, professor, Korea University in Seoul, South Korea. He is also the president of the ITA-AITES. In a sweeping presentation, Lee walked the packed audience through some of the most fascinating and challenging projects in his home country. Among the projects he spoke about were Korea?s longest railway tunnel, the Solahn Tunnel and the Inje Tunnel, a freeway tunnel that is 11.94 km (7.4 miles) long.

Jan 1, 2012

By H. F. Feldmann

This work was done to provide thermodynamic, electrical, physical, and compositional data on the seeded combustion plasmas of seven coals for the design of MHD generators. The systems were assumed to be at equilibrium, and the design data were generated by solving for the composition of both gas and liquid phases with a digital computer. The coals reported in this study include a western subbituminous, a Pennsylvania anthracite, and five representative bituminous coals. The data include dewpoint temperatures of both slag and seed. A Mollier diagram for each coal is given to allow graphical generator calculations.

Jan 1, 1970

By Lloyd M. English

During the past 30 years, the research arena has changed significantly in all fields, mining included. The relative representation of the topics of research, how the research is performed and who has performed the research have all changed. Although there are a lot of subjective ideas and anecdotal "analyses" concerning these changes, there has been no actual study of these trends to verify the facts. This study was divided into six five-¬year periods for the purposes of comparison. Some of the trends analyzed are co-authorship, research areas, research sponsors and cooperative efforts. In today&apos;s research arena, 30 years is a long time. Technology has advanced more rapidly than in any time previously and that pace continues to increase. There are more researchers, more tools for research and an increasing number of companies, agencies and institutions engaged in research. The pace of change and its impact is often discussed and debated at professional meetings and in institutions that engage in research. These conversations will often influence the research decisions of the participants in directions to take or subjects to pursue.

Jan 1, 1995

By H. B. Carroll

The performance of commercially available portable instrumentation for detecting nitrogen dioxide, sulfur dioxide, and hydrogen sulfide was evaluated. Length-of-stain detector tubes from several manufacturers were included in the study. The instruments were evaluated in atmospheres with 50-and 80-percent relative humidities at 75° F and containing test gas concentrations of 0.1, 0.25, 0.50, 1.0, 1.5, and 2.0 times the threshold limit values. The results from the gas analyzers were correlated with the known contaminant concentration by calculating and plotting an estimated line of regression, confidence limits, and correlation coefficient for each detector system. An increase in the relative humidity from 50 to 80 percent at /5° F changed the instrument response to the contaminants. The uncertainties in detection precision reported are for the observer-instrument system. The main difference or inconsistency in toxic gas concentrations determined with length-of-stain tubes resulted from the observer&apos;s interpretation of the results rather than from a predominant difference in the tubes.

Jan 1, 1975

By Y. L. Sun

The feasibility of using the ultrasonic wave attenuation method for measuring in-situ stress is examined theoretically and experimentally. The theoretical analyses show that for a given rock type the relation between stress and attenuation coefficient ratio can be approximated closely by second-order polynomials. Combining the elastic and statistical theories, the magnitude and direction of the existing principal stresses can be predicted by using the relations between stress and attenuation coefficient ratio obtained in the calibration of core specimens. Several experiments are conducted in the laboratory on two types of rock. The experimental study consists of two parts: the attenuation-coefficient measurements in core specimens under uniaxial stress and the attenuation coefficient measurements in boreholes drilled through blocks of sandstone and limestone subjected to uniaxial compressional stress. Compressional waves are used exclusively in the measurements.

Jan 1, 1989

By W. F. Faragher

The principal equipment in the catalyst plants at Ludwigshafen-Oppau was inspected and is presented in the form of flow sheets for the manufacture of four of the principal catalysts. The equipment is in many cases of special design rather than stock items that was built by the company and modified in the coarse of the growth of the high-pressure synthesis of hydrocarbons in Germany. It is believed that if the manufacture of catalysts were to be undertaken elsewhere, the selection of equipment for the operations involved could be made successfully from the guidance furnished by this rather general report. Five additional catalysts are described, also. II. CATALYST 5058 FROM FRESH TUNGSTIC ACID In a supply tank of about 2,000 liters capacity, 500 kg. of tungstic acid (W03.H2O) that contains about 92-93 percent of W03 is dissolved at 60-70° C. in 1,500 liters of mother liquor. The solution is-effected by stirring for about 1-1/2 hours. The mother liquor is obtained from a previous, lot of catalyst and is first adjusted to a concentration of 13 percent 1H3 by passing in gaseous ammonia. The solution is allowed to stand without stirring for 1 hour, then is pumped into the saturating vessel through a cloth filter (three-quarters hr. to one hr.). The saturator is purged with H2S and thereafter the solution, which has been cooled to about 75° C., is heated in an atmosphere of hydrogen sulfide with stirring to about 70° C. This charge is slowly cooled to 50°, and then more rapidly to about 20° C. (time of cooling 6-7 hours).

Jan 1, 1946